LO-3-61
Product Specifications
Target
E1/E2/E3 Enzyme|||Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic|||Ubiquitination
Bioactivity
LO-3-61 is a JQ-1 analog featuring a truncated fumarylamide group, classified as a BRD4 degrader with PROTAC (protein degradation targeting chimera) properties. It promotes the degradation of both long and short BRD4 isoforms via a CUL4DCAF16-dependent pathway. In MDA-MB-231 cells, LO-3-61 exhibits selectivity in degrading BRD3 and BRD4.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
169182 100 µg
PSA (Prostate-specific antigen, gamma-seminoprotein, Kallikrein-3, KLK3)
Ask
View Details 
