PPARγ agonist 19
Product Specifications
Target
PPAR, COX
Related Pathways
Neuroscience, DNA Damage/DNA Repair, Immunology/Inflammation, Metabolism
Bioactivity
PPARγ agonist19 (Compound 5e) is a PPARγ agonist with an IC50 of 11.27 μM for COX-1 and 0.05 μM for COX-2. It enhances glucose uptake in rat hemidiaphragm assays more effectively than pioglitazone. Additionally, PPARγ agonist19 reduces hyperglycemia and insulin resistance in type 2 diabetic rat models and protects against renal and lipid damage caused by metabolic dysfunction.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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