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PPAR? agonist 19

Product Specifications

Target

PPAR|||COX

Related Pathways

Neuroscience|||DNA Damage/DNA Repair|||Immunology/Inflammation|||Metabolism

Bioactivity

PPAR? agonist19 (Compound 5e) is a PPAR? agonist with an IC50 of 11.27 ?M for COX-1 and 0.05 ?M for COX-2. It enhances glucose uptake in rat hemidiaphragm assays more effectively than pioglitazone. Additionally, PPAR? agonist19 reduces hyperglycemia and insulin resistance in type 2 diabetic rat models and protects against renal and lipid damage caused by metabolic dysfunction.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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