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AAK1-IN-10

Product Specifications

CAS Number

3083494-45-2

Target

AAK1 (AP2 associated kinase 1)

Related Pathways

Neuroscience

Bioactivity

AAK1-IN-10 (Compound 1-2) is an AAK1 inhibitor with significant enzymatic inhibition of AAK1 (IC50: 9.62 nM) . Its primary mechanism involves inhibiting adaptor-associated kinase 1 (AAK1) activity. AAK1-IN-10 exhibits minimal cardiotoxicity (IC50 = 13.7 ?M) and can be utilized in research for diabetic neuralgia and postherpetic neuralgia.

Smiles

C(F)(F)C1=NC(=CC=C1OC[C@@](C[C@@](CO)(C)O)(C)N)C=2C=C(C(F)F)N=CC2

Molecular Formula

C19H23F4N3O3

Molecular Weight

417.4

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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