AAK1-IN-10
Product Specifications
CAS Number
3083494-45-2
Target
AAK1 (AP2 associated kinase 1)
Related Pathways
Neuroscience
Bioactivity
AAK1-IN-10 (Compound 1-2) is an AAK1 inhibitor with significant enzymatic inhibition of AAK1 (IC50: 9.62 nM) . Its primary mechanism involves inhibiting adaptor-associated kinase 1 (AAK1) activity. AAK1-IN-10 exhibits minimal cardiotoxicity (IC50 = 13.7 ?M) and can be utilized in research for diabetic neuralgia and postherpetic neuralgia.
Smiles
C(F)(F)C1=NC(=CC=C1OC[C@@](C[C@@](CO)(C)O)(C)N)C=2C=C(C(F)F)N=CC2
Molecular Formula
C19H23F4N3O3
Molecular Weight
417.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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