STING agonist-43
Product Specifications
CAS Number
2882097-31-4
Target
STING
Related Pathways
Immunology/Inflammation
Bioactivity
STINGagonist-43 (Compound 67) is a selective STING agonist with an EC50 of 20.53 μM. It selectively enhances the cGAMP-dependent STING pathway activation by modulating STING oligomerization. STINGagonist-43 demonstrates antitumor activity in a B16.F10 mouse melanoma model and can be utilized in cancer immunotherapy research.
Smiles
O=C(OCC)CN1C2=CC=C(C=C2C(=O)C3=CC(OC)=C(C(=C31)C)C)C
Molecular Formula
C21H23NO4
Molecular Weight
353.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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