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STING agonist-43

Product Specifications

CAS Number

2882097-31-4

Target

STING

Related Pathways

Immunology/Inflammation

Bioactivity

STINGagonist-43 (Compound 67) is a selective STING agonist with an EC50 of 20.53 ?M. It selectively enhances the cGAMP-dependent STING pathway activation by modulating STING oligomerization. STINGagonist-43 demonstrates antitumor activity in a B16.F10 mouse melanoma model and can be utilized in cancer immunotherapy research.

Smiles

O=C(OCC)CN1C2=CC=C(C=C2C(=O)C3=CC(OC)=C(C(=C31)C)C)C

Molecular Formula

C21H23NO4

Molecular Weight

353.41

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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