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KRASG12C ligand-1

Product Specifications

CAS Number

3053689-44-1

Target

Ligands for Target Protein for PROTAC, Ras

Related Pathways

MAPK, PROTAC

Bioactivity

KRASG12C ligand-1 is a PROTAC target protein ligand utilized in synthesizing PROTAC YN14-H. YN14-H acts as a PROTAC degrader targeting KRASG12C, exhibiting antitumor activity.

Smiles

O=C1N(C=2C(C(=N1)N3[C@@H](C)CN(C(C=C)=O)CC3)=CC(F)=C(N2)C4=C(OCC5CCNCC5)C=CC=C4F)C6=C(C(C)C)N=CC=C6C

Molecular Formula

C36H41F2N7O3

Molecular Weight

657.75

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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