TK-684
Product Specifications
Target
Apoptosis, Phosphatase
Related Pathways
Apoptosis, Metabolism
Bioactivity
TK-684 is a potent and selective allosteric inhibitor of SHP2, with IC50 values of 2.1 nM for SHP2WT and greater than 1000 nM for SHP2PTP. It inhibits cell proliferation and induces apoptosis (apoptosis) . Additionally, TK-684 reduces the protein expression of p-AKT and p-ERK.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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