ISM5939
Product Specifications
CAS Number
2965301-60-2
Target
PDE
Related Pathways
Metabolism
Bioactivity
ISM5939 is an orally active and selective ENPP1 inhibitor, with an IC50 value of 0.63 nM for 2,3-cGAMP degradation and 9.28 nM for ATP hydrolysis. Additionally, ISM5939 exhibits antitumor activity.
Smiles
O=S(=O)(N)C1=CN=C(C(F)=C1)CN2C(=NC=3C=NC(OC)=C(C4=CC=CC=C4)C32)C
Molecular Formula
C20H18FN5O3S
Molecular Weight
427.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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