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ISM5939

Product Specifications

CAS Number

2965301-60-2

Target

PDE

Related Pathways

Metabolism

Bioactivity

ISM5939 is an orally active and selective ENPP1 inhibitor, with an IC50 value of 0.63 nM for 2,3-cGAMP degradation and 9.28 nM for ATP hydrolysis. Additionally, ISM5939 exhibits antitumor activity.

Smiles

O=S(=O)(N)C1=CN=C(C(F)=C1)CN2C(=NC=3C=NC(OC)=C(C4=CC=CC=C4)C32)C

Molecular Formula

C20H18FN5O3S

Molecular Weight

427.45

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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