1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA
Product Specifications
CAS Number
65446-08-4
Target
LPL Receptor
Related Pathways
GPCR/G Protein
Bioactivity
1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA is a phospholipid that contains arachidonic acid at the sn-1 position, serving as a precursor to 1-Monoarachidin. It binds with the LPA2/EDG4 receptor and can inhibit the secretion of TNF-α and IL-6 induced by LPS in wild-type dendritic cells but does not affect Lpa2-/- dendritic cells. Additionally, it reduces the differentiation of HT-29 human colon cancer cells into goblet cells in the presence of sodium butyrate.
Smiles
C(OC[C@H](COP(=O)(O)O)O)(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O
Molecular Formula
C23H39O7P
Molecular Weight
458.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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