Y2641
Product Specifications
Target
TNF|||RANKL/RANK
Related Pathways
Apoptosis|||NF-?B
Bioactivity
Y2641, a tetrahydro ?-carboline derivative, is an orally active dual inhibitor of RANKL and TNF-?, with Kd values of 3.984 ?M and 18.59 ?M respectively. It suppresses RANKL-induced osteoclastogenesis and exhibits anti-inflammatory and cartilage-protective properties. Y2641 is applicable in osteoarthritis research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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