2-5A

Product Specifications

CAS Number

65954-93-0

Target

DNA/RNA Synthesis|||RSV

Related Pathways

DNA Damage/DNA Repair|||Microbiology/Virology|||Cell Cycle/Checkpoint

Bioactivity

2-5A is a 5'-triphosphorylated (2',5') oligoadenylate. It acts as an immune messenger capable of enhancing RNase L immunity. By binding to RNase L and activating its endoribonuclease activity, 2-5A degrades viral mRNA and inhibits protein synthesis. This compound is useful in research on respiratory syncytial virus (RSV) and cancer.

Smiles

O(P(OC[C@H]1O[C@H]([C@H](OP(OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=4C(N=C3)=C(N)N=CN4)(=O)O)[C@@H]1O)N5C=6C(N=C5)=C(N)N=CN6)(=O)O)[C@H]7[C@@H](O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]7O)N8C=9C(N=C8)=C(N)N=CN9