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HSD17B13-IN-104

Product Specifications

CAS Number

3075100-76-1

Target

Dehydrogenase

Related Pathways

Metabolism

Bioactivity

HSD17B13-IN-104 (Compound 32) is an orally active and potent inhibitor of HSD17B13 with high selectivity (IC50=2.5 nM) . It modulates liver lipid metabolism by inhibiting the SREBP-1c/FAS pathway and blocks the enzymatic activity of HSD17B13 to alleviate hepatic lipid accumulation. HSD17B13-IN-104 shows potential for research in metabolic dysfunction-associated fatty liver disease.

Smiles

O=C(C=1SC(=NC1C)C=2C=C(F)C(F)=C(O)C2F)N(CC3=CC=C(Cl)C=C3)C(C)C

Molecular Formula

C21H18ClF3N2O2S

Molecular Weight

454.89

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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