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EED-IN-3

Product Specifications

CAS Number

3051817-48-9

Target

Histone Methyltransferase, Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic

Bioactivity

EED-IN-3 is an orally active inhibitor of EED. It effectively binds with EED (IC50 = 0.62 μM) to inhibit PRC2 and reduces H3K27me3 levels. EED-IN-3 selectively inhibits PC3 cells with an IC50 of 3.69 μM and significantly suppresses colony formation and migration. This compound is useful for prostate cancer research.

Smiles

O=C(NCCCOC(C)C)C1=CC(=NN(C1=O)C2=CC=C(OC)C=C2)C=3C=CC(OC)=CC3

Molecular Formula

C25H29N3O5

Molecular Weight

451.52

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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