EED-IN-3
Product Specifications
CAS Number
3051817-48-9
Target
Histone Methyltransferase|||Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic
Bioactivity
EED-IN-3 is an orally active inhibitor of EED. It effectively binds with EED (IC50 = 0.62 ?M) to inhibit PRC2 and reduces H3K27me3 levels. EED-IN-3 selectively inhibits PC3 cells with an IC50 of 3.69 ?M and significantly suppresses colony formation and migration. This compound is useful for prostate cancer research.
Smiles
O=C(NCCCOC(C)C)C1=CC(=NN(C1=O)C2=CC=C(OC)C=C2)C=3C=CC(OC)=CC3
Molecular Formula
C25H29N3O5
Molecular Weight
451.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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