JP-163-16
Product Specifications
Target
PROTACs|||Apoptosis|||NF-?B
Related Pathways
Apoptosis|||PROTAC|||NF-?B
Bioactivity
JP-163-16 is a RelA/p65 PROTAC degrader. It selectively reduces the expression of RelA/p65 in cells via a proteasome-dependent mechanism. JP-163-16 induces apoptosis by inhibiting the NF-?B signaling pathway. This compound is applicable for research on RelA/p65-dependent tumors, such as chronic lymphocytic leukemia (CLL) .
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
123366-ML405 100 µL
ANXA5 (Annexin A5, Annexin-5, Annexin V, Lipocortin V, Endonexin II, Calphobindin I, CBP-I, Placental Anticoagulant Protein I, PAP-I, Placental Anticoagulant Protein 4, PP4, Thromboplastin Inhibitor, Vascular Anticoagulant-alpha, VAC-alpha, Anchorin CII, PP4, ENX2, ANX5, Annexin V, ) (MaxLight 405) discontinued
Ask
View Details 
NBP2-12222R 0.1 mL
Mouse Monoclonal CXCL13/BLC/BCA-1 Antibody (MM0212-12A2) [DyLight 550]
Ask
View Details