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JP-163-16

Product Specifications

Target

PROTACs|||Apoptosis|||NF-?B

Related Pathways

Apoptosis|||PROTAC|||NF-?B

Bioactivity

JP-163-16 is a RelA/p65 PROTAC degrader. It selectively reduces the expression of RelA/p65 in cells via a proteasome-dependent mechanism. JP-163-16 induces apoptosis by inhibiting the NF-?B signaling pathway. This compound is applicable for research on RelA/p65-dependent tumors, such as chronic lymphocytic leukemia (CLL) .

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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