ROR1-IN-3
Product Specifications
Target
Akt, NF-κB, Apoptosis, mTOR, ROR
Related Pathways
Cytoskeletal Signaling, Metabolism, PI3K/Akt/mTOR signaling, NF-κB, Apoptosis
Bioactivity
ROR1-IN-3 (Compound 24d) is a potent and highly selective inhibitor of the ROR1 kinase, with an IC50 of 17.6 nM. It demonstrates significant antitumor activity and ROR1 inhibition both in vitro and in vivo, exhibiting strong antiproliferative effects. ROR1-IN-3 induces apoptosis in cancer cell lines and inhibits downstream AKT/mTOR and NF-κB signaling pathways. This compound is applicable for antitumor research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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