GT-02216
Product Specifications
CAS Number
2648407-76-3
Target
Glycosidase
Related Pathways
Metabolism
Bioactivity
GT-02216 is capable of binding allosterically to GCase, thereby enhancing its function. In primary human fibroblasts, it increases GCase activity and decreases Tau accumulation in mutant GBA1 fibroblasts. Additionally, GT-02216 offers protection to hippocampal primary neurons exposed to Tau oligomer in a rat model.
Smiles
O=C(C1=NC(N)=CC(=C1)NC=2C=CC=CC2O)N3CCN(C=4C=CC=CC4)CC3
Molecular Formula
C22H23N5O2
Molecular Weight
389.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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