Z218484536
Product Specifications
CAS Number
1223877-07-3
Target
Phosphatase
Related Pathways
Metabolism
Bioactivity
Z218484536 is a selective phosphoserine phosphatase (PSPH) inhibitor that can penetrate the blood-brain barrier. It binds to PSPH with an affinity (Kd) of approximately 0.23 μM. By doing so, Z218484536 reduces levels of L-serine and D-serine in astrocytes. It also inhibits spontaneous seizures without causing significant side effects and demonstrates effective antiepileptic properties in the temporal lobe epilepsy (TLE) model.
Smiles
O=C(N)NN=CC1=CNN=C1C=2C=CC(F)=CC2
Molecular Formula
C11H10FN5O
Molecular Weight
247.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUB0792-500 1x 500 µL
IgA Secretory Component (ECM1/792), 0.2mg/mL
Sign In for Pricing
View Details ![MCM2 Mouse Monoclonal Antibody [Clone ID: OTI1C7]](https://cdn.genprice.uk/products/937/68dd18b9061270361e907d78/imageurl/cf805621.webp)
![PE Anti-Mouse CD279/PD-1 Antibody[29F.1A12]](https://cdn.genprice.uk/products/763/68dd149d061270361e7cfa02/imageurl/e-ab-f1131ud.webp)