SARS-CoV-2-IN-113
Product Specifications
CAS Number
455304-63-9
Target
Angiotensin-converting Enzyme (ACE) |||SARS-CoV
Related Pathways
Metabolism|||Microbiology/Virology
Bioactivity
SARS-CoV-2-IN-113 (Compound 24) is a sulfonyl hydrazine derivative that exhibits antiviral activity against SARS-CoV-2 infection, with an IC50 of 8.320 ?M. It effectively inhibits the entry and replication of SARS-CoV-2 by downregulating genes and proteins such as Spike, ACE-2, and RdRp. SARS-CoV-2-IN-113 shows high selectivity and low cytotoxicity, making it a valuable candidate for COVID-19 research.
Smiles
O=S(=O)(NN=CC1=CC=C(O)C(O)=C1O)C2=CC=C(C=C2)C
Molecular Formula
C14H14N2O5S
Molecular Weight
322.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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