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SARS-CoV-2-IN-113

Product Specifications

CAS Number

455304-63-9

Target

Angiotensin-converting Enzyme (ACE) |||SARS-CoV

Related Pathways

Metabolism|||Microbiology/Virology

Bioactivity

SARS-CoV-2-IN-113 (Compound 24) is a sulfonyl hydrazine derivative that exhibits antiviral activity against SARS-CoV-2 infection, with an IC50 of 8.320 ?M. It effectively inhibits the entry and replication of SARS-CoV-2 by downregulating genes and proteins such as Spike, ACE-2, and RdRp. SARS-CoV-2-IN-113 shows high selectivity and low cytotoxicity, making it a valuable candidate for COVID-19 research.

Smiles

O=S(=O)(NN=CC1=CC=C(O)C(O)=C1O)C2=CC=C(C=C2)C

Molecular Formula

C14H14N2O5S

Molecular Weight

322.34

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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