XSJ110
Product Specifications
CAS Number
203923-65-3
Target
Apoptosis|||Topoisomerase
Related Pathways
DNA Damage/DNA Repair|||Apoptosis
Bioactivity
XSJ110 is a potent irreversible inhibitor of topoisomerase I (Topo I) with an IC50 value of 0.133 ?M. It halts the topoisomerization process of DNA, leading to double-strand breaks and inducing cell cycle arrest in the G0/G1 phase, ultimately causing apoptosis in tumor cells. XSJ110 shows potential for research in ampullary carcinoma (AC) .
Smiles
C(CC)(=O)C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@](CC)(O)C(=O)OC4)=NC=5C1=CC=CC5
Molecular Formula
C23H20N2O5
Molecular Weight
404.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6215820-01 0.1 mL
ALOX15 (Arachidonate 15-Lipoxygenase, 15-LOX-1, 15-LOX2) (MaxLight 550)
Ask
View Details 
MBS6215820-02 5x 0.1 mL
ALOX15 (Arachidonate 15-Lipoxygenase, 15-LOX-1, 15-LOX2) (MaxLight 550)
Ask
View Details