Amb929
Product Specifications
CAS Number
438196-25-9
Target
SARS-CoV
Related Pathways
Microbiology/Virology
Bioactivity
Amb929 (ZINC000002782982), an nsp3 ligand, is a drug active against SARS-CoV-2. It inhibits the replication of SARS-CoV-2-mNG in VeroE6 cells with an EC50 value of 34.7 µM. Amb929 exhibits limited to moderate cytotoxicity in VeroE6 cells (CC50: 281 µM) and also suppresses the replication of SARS-CoV-2-mNG in human airway epithelium (HAE) .
Smiles
O=C(OC)C1=CC=C(C=C1)NC(=S)NC(=O)C2=CC(=NC=3C=CC=CC32)C=4C=CC=C(OCC(C)C)C4
Molecular Formula
C29H27N3O4S
Molecular Weight
513.61
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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T0900-09D 100 µg
TNKS2 (Tankyrase-2, TANK2, Poly [ADP-ribose] Polymerase 5B, Tankyrase II, TNKS-2, TRF1-interacting Ankyrin-related ADP-ribose Polymerase 2, TRF1-interacting Ankyrin-related, ADP-ribose Polymerase 2, Tankyrase-like Protein, Tankyrase-related Protein, PARP5B, TANK2, TNKL)
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