Topoisomerase inhibitor 6
Product Specifications
CAS Number
2987726-03-2
Target
Topoisomerase, Antibacterial
Related Pathways
DNA Damage/DNA Repair, Microbiology/Virology
Bioactivity
Topoisomerase inhibitor6 (Compound REDX05931) is a dual irreversible inhibitor of DNA gyrase and topoisomerase IV, with an MIC of 0.06 μg/mL against fluoroquinolone-resistant S. aureus. It halts the DNA strand breaking-rejoining process, causing lethal DNA damage, and holds potential for studying infections caused by Gram-positive bacteria such as S. aureus and S. pneumoniae.
Smiles
ClC1=C2C(C3=C(C(=O)N2C4CC4)N=C(C)O3)=CC(F)=C1N5C[C@]([C@H](C)N)(CC5)[H]
Molecular Formula
C20H22ClFN4O2
Molecular Weight
404.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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