AF151
Product Specifications
Target
Apoptosis, PROTACs, Bcl-2 Family, Others
Related Pathways
PROTAC, Apoptosis, Others
Bioactivity
AF151 is a METTL3 PROTAC degrader with a DC50 of 0.43 μM in MOLM-13 cells. It inhibits cell growth by significantly degrading METTL3 protein and reducing m6A levels. AF151 induces apoptosis and decreases Bcl-2 protein levels. This compound is applicable in research related to cancers such as acute myeloid leukemia (AML) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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