EGFR-IN-163
Product Specifications
Target
EGFR, Apoptosis
Related Pathways
Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Bioactivity
EGFR-IN-163 (Compound 13) is a competitive inhibitor of the epidermal growth factor receptor (EGFR) with an IC50 of 0.079 μM and selective inhibition on HER-2. It induces apoptosis in tumor cells and causes cell cycle arrest at the G2/M phase. EGFR-IN-163 shows promise for investigating estrogen receptor-positive (ER+) breast cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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