CLM296
Product Specifications
CAS Number
3067837-25-3
Target
Dehydrogenase
Related Pathways
Metabolism
Bioactivity
CLM296 is a potent and selective inhibitor of ALDH1A3, with an IC50 of 2 nM. It does not exhibit off-target effects on the highly homologous ALDH1A1 isoform. CLM296 is capable of inhibiting ALDH1A3-driven breast cancer metastasis and can be utilized in the study of triple-negative breast cancer (TNBC) .
Smiles
O=C(C=1C=CC(=CC1)C=2C=C(C=3C=CC(=CC3)C(=O)C)C4=NC(=CN4C2)C=5C=CC=CC5)C
Molecular Formula
C29H22N2O2
Molecular Weight
430.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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