TFCA
Product Specifications
CAS Number
895700-18-2
Target
Liver X Receptor
Related Pathways
Metabolism
Bioactivity
TFCA is a liver X receptor α (LXRα) antagonist. It inhibits the coactivation of ligand-activated LXRα and suppresses the transcriptional expression of downstream target genes involved in fatty acid synthesis. By selectively inhibiting LXRα in the liver, TFCA reduces ligand-induced lipogenesis and fatty liver.
Smiles
O=C(C=CC1=CC=C(OC)C(OC)=C1)NC2=CC=C(C=C2)C(F)(F)F
Molecular Formula
C18H16F3NO3
Molecular Weight
351.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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