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TFCA

Product Specifications

CAS Number

895700-18-2

Target

Liver X Receptor

Related Pathways

Metabolism

Bioactivity

TFCA is a liver X receptor α (LXRα) antagonist. It inhibits the coactivation of ligand-activated LXRα and suppresses the transcriptional expression of downstream target genes involved in fatty acid synthesis. By selectively inhibiting LXRα in the liver, TFCA reduces ligand-induced lipogenesis and fatty liver.

Smiles

O=C(C=CC1=CC=C(OC)C(OC)=C1)NC2=CC=C(C=C2)C(F)(F)F

Molecular Formula

C18H16F3NO3

Molecular Weight

351.32

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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