NSC-323241
Product Specifications
CAS Number
79514-43-5
Target
Anti-infection
Related Pathways
Microbiology/Virology
Bioactivity
NSC-323241 is a potent inhibitor of STT3A-mediated mega protein complex assembly. It disrupts the large endoplasmic reticulum (ER) complexes localized by STT3A during dengue virus (DENV) and Zika virus (ZIKV) infections. NSC-323241 interferes with the binding of the STT3A subcomplex to viral non-structural proteins (such as NS2B, NS3) and host transporter proteins, thus impairing the formation of the viral replication microenvironment. This compound holds promise for researching flavivirus infections, including dengue and Zika viruses.
Smiles
[Se]=C(NN=C(C1=NC=CC=C1)C)N2CC3CCC(C2)CC3
Molecular Formula
C16H22N4Se
Molecular Weight
349.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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