Osimertinib dimer
Product Specifications
CAS Number
2564638-97-5
Target
Others
Related Pathways
Others
Bioactivity
Osimertinibdimer is the dimer of Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutation-selective EGFR inhibitor, effectively suppressing L858R (IC50=12 nM) and L858R/T790M (IC50=1 nM) EGFR. It addresses resistance to EGFR inhibitors mediated by the T790M mutation in lung cancer.
Smiles
O=C(C=C)NC1=CC(NC=2N=CC=C(N2)C3=CN(C=4C=CC=CC34)C)=C(OC)C=C1N(C)CC[N+](C)(C)CCC(=O)NC5=CC(NC=6N=CC=C(N6)C7=CN(C=8C=CC=CC78)C)=C(OC)C=C5N(C)CCN(C)C
Molecular Formula
C56H67N14O4
Molecular Weight
1000.22
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
043858-APC 200 µL
WDR85, NT (WDR85, C9orf112, WD repeat-containing protein 85) (APC) discontinued
Ask
View Details 
![CDC25C Rabbit Monoclonal Antibody [Clone ID: 23GB3430]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)