PARP1-IN-39
Product Specifications
CAS Number
3054988-47-2
Target
PARP
Related Pathways
DNA Damage/DNA Repair|||Chromatin/Epigenetic
Bioactivity
PARP1-IN-39 is an inhibitor of PARP1, with an IC50 value of 0.22 nM. In human breast cancer cells, its IC50 is 1.57 nM. PARP1-IN-39 is applicable for studying cancers associated with DNA repair deficiencies, such as breast, ovarian, pancreatic, and prostate cancers, particularly those with BRCA1/2 mutations.
Smiles
O=C(NCC)C1=NC(F)=C(C=C1)N2N=C3C(=C2)CN(C3)CC4=CC=C5C(NC(=O)C6=C(F)C=NN56)=C4F
Molecular Formula
C24H19F3N8O2
Molecular Weight
508.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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