Erufosine
Product Specifications
CAS Number
202867-33-2
Target
Raf, Ras, Akt, p38 MAPK, PI3K
Related Pathways
PI3K/Akt/mTOR signaling, MAPK, Cytoskeletal Signaling
Bioactivity
Erufosine is an inhibitor of the PI3K/Akt and Ras/Raf/MAPK signaling pathways. It suppresses the activity of breast cancer cell lines MCF-7 and MDA-MB 231 with an IC50 of 40.95/40.8 μM, respectively. Erufosine reduces phosphorylation of PI3K (p85), Akt (PKB), and cRaf, making it applicable in research on breast cancer and myeloid leukemia.
Smiles
P(OCCCCCCCCCCCC/C=C\CCCCCCCC)(OCCC[N+](C)(C)C)(=O)[O-]
Molecular Formula
C28H58NO4P
Molecular Weight
503.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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