What is the catalog number for CC-647?

The catalog number for CC-647 is T211005.

What sizes are available for CC-647?

CC-647 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does CC-647 come in?

CC-647 is available in 2 different pack sizes.

CC-647 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CC-647?

CC-647 is manufactured by Molfinity.

What is the estimated delivery time for CC-647?

Estimated delivery time for CC-647 is approximately 10 business day(s), depending on your location.

CC-647

Product Specifications

CAS Number

1061605-35-3

Target

E1/E2/E3 Enzyme, Molecular Glues

Related Pathways

PROTAC, Ubiquitination

Bioactivity

CC-647 is a molecular glue modulator targeting the Cereblon (CRBN) E3 ubiquitin ligase. It enhances the interaction between CRBN and ZBTB16, as well as its oncogenic fusion protein RARα-ZBTB16, with a half-maximal degradation concentration (DC50) of 103 nM for ZBTB16. CC-647 holds potential for studying ZBTB16-RARα related acute promyelocytic leukemia (APL) .