What is the catalog number for AR antagonist 15?

The catalog number for AR antagonist 15 is T210996.

What sizes are available for AR antagonist 15?

AR antagonist 15 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does AR antagonist 15 come in?

AR antagonist 15 is available in 2 different pack sizes.

Is AR antagonist 15 in stock?

AR antagonist 15 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AR antagonist 15?

AR antagonist 15 is manufactured by Molfinity.

What is the estimated delivery time for AR antagonist 15?

Estimated delivery time for AR antagonist 15 is approximately 10 business day(s), depending on your location.

AR antagonist 15

Product Specifications

CAS Number

1790308-86-9

Target

Apoptosis, Androgen Receptor

Related Pathways

Endocrinology/Hormones, Apoptosis

Bioactivity

AR antagonist 15 is an orally active androgen receptor (AR) antagonist with an IC50 of 97 nM for ART787A. It impairs AR nuclear translocation, hinders AR homodimerization, and inhibits AR-regulated gene transcription by competitively binding to the ligand-binding pocket. AR antagonist 15 significantly reduces prostate-specific antigen (PSA) levels and induces apoptosis by decreasing the expression of apoptosis-related proteins. This compound is useful for prostate cancer research.