DGK-IN-9
Product Specifications
CAS Number
3081525-23-4
Target
Interleukin, Others
Related Pathways
Others, Immunology/Inflammation
Bioactivity
DGK-IN-9 (Compound 15) is an orally active and selective inhibitor of DGKζ with an IC50 of 6.1 nM. It is capable of activating IL-2 expression in Jurkat-IL2 nanoluc cells with an EC50 of 153 nM. DGK-IN-9 is applicable in tumor research.
Smiles
O=C(NC1=CC=C(OC=2C=CC=CC2F)C(=C1N(C)CCNC)C(F)(F)F)C3=NC(=CS3)C=4C=NN=CC4
Molecular Formula
C25H22F4N6O2S
Molecular Weight
546.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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