PDE4-IN-28
Product Specifications
Target
PDE, TNF, Antibacterial, NO Synthase
Related Pathways
Immunology/Inflammation, Apoptosis, Microbiology/Virology, Metabolism
Bioactivity
PDE4-IN-28 (Compound G1) is an inhibitor of PDE4D, with an IC50 of 29 nM. It suppresses the production of TNF-α and NO, with IC50 values of 13.32 μM and 2.32 μM, respectively. In a rat pressure ulcer (PU) model, PDE4-IN-28 exhibits anti-inflammatory, antibacterial, and analgesic properties, while promoting HUVEC cell migration to enhance wound healing.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6413463-01 0.1 mL
CYP2E1 (Cytochrome P450 Enzyme 2E1, CPE1, CYP2E, P450-J, P450C2E) (Biotin)
Sign In for Pricing
View Details MBS6413463-02 5x 0.1 mL
CYP2E1 (Cytochrome P450 Enzyme 2E1, CPE1, CYP2E, P450-J, P450C2E) (Biotin)
Sign In for Pricing
View Details 
MBS1029671-01 0.02 mg (E-Coli)
Recombinant Rhodopseudomonas palustris 10 kDa chaperonin 2 (groS2)
Sign In for Pricing
View Details MBS1029671-02 0.1 mg (E-Coli)
Recombinant Rhodopseudomonas palustris 10 kDa chaperonin 2 (groS2)
Sign In for Pricing
View Details MBS1029671-03 0.02 mg (Yeast)
Recombinant Rhodopseudomonas palustris 10 kDa chaperonin 2 (groS2)
Sign In for Pricing
View Details MBS1029671-04 0.1 mg (Yeast)
Recombinant Rhodopseudomonas palustris 10 kDa chaperonin 2 (groS2)
Sign In for Pricing
View Details