What is the catalog number for Keap1-IN-2?

The catalog number for Keap1-IN-2 is T210959.

What sizes are available for Keap1-IN-2?

Keap1-IN-2 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does Keap1-IN-2 come in?

Keap1-IN-2 is available in 2 different pack sizes.

Is Keap1-IN-2 in stock?

Keap1-IN-2 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Keap1-IN-2?

Keap1-IN-2 is manufactured by Molfinity.

What is the estimated delivery time for Keap1-IN-2?

Estimated delivery time for Keap1-IN-2 is approximately 10 business day(s), depending on your location.

Keap1-IN-2

Product Specifications

CAS Number

3066895-41-5

Target

Nrf2

Related Pathways

Immunology/Inflammation

Bioactivity

Keap1-IN-2 (Compound 164) is an inhibitor of KEAP1 with an IC50 of 2 nM. It indirectly activates Nrf2 by blocking KEAP1, thereby enhancing cellular antioxidant capacity. By preventing KEAP1-mediated degradation of Nrf2, Keap1-IN-2 promotes the accumulation and nuclear translocation of Nrf2. This compound is used in research on diseases related to oxidative stress, such as inflammatory bowel disease, Crohn's disease, and ulcerative colitis, which are immune-related conditions.