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MAO-B-IN-44

Product Specifications

CAS Number

1454707-25-5

Target

Monoamine Oxidase

Related Pathways

Neuroscience

Bioactivity

MAO-B-IN-44 (Compound 4n) is a selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 1.01 μM, demonstrating weak inhibition of MAO-A (IC50=14.4 μM) . It reduces the degradation of neurotransmitters like dopamine and holds potential for research into neurodegenerative diseases such as Parkinson's disease, which are associated with MAO-B abnormalities.

Smiles

O=C(OCC)C1=C(NC2=CC=C(OC)C=C2)CC(C3=CC=C(C=C3)N(=O)=O)N(C4=CC=C(OC)C=C4)C1C5=CC=C(C=C5)N(=O)=O

Molecular Formula

C34H32N4O8

Molecular Weight

624.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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