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SARM1-IN-6

Product Specifications

CAS Number

3080315-51-8

Target

TLR

Related Pathways

Immunology/Inflammation

Bioactivity

SARM1-IN-6 (Compound 17a) is a brain-penetrant orthosteric inhibitor of SARM1. It exhibits an IC50 of 14 nM against NAM and 74 nM against HEK cells.

Smiles

O=C1N(C23CC(C2)(C3)C=4C=CN=CC4)CC[C@@H](C1)C=5C=C(F)C(F)=NC5

Molecular Formula

C20H19F2N3O

Molecular Weight

355.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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