What is the catalog number for KI-TOX-A3?

The catalog number for KI-TOX-A3 is T210914.

What sizes are available for KI-TOX-A3?

KI-TOX-A3 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does KI-TOX-A3 come in?

KI-TOX-A3 is available in 2 different pack sizes.

Is KI-TOX-A3 in stock?

KI-TOX-A3 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures KI-TOX-A3?

KI-TOX-A3 is manufactured by Molfinity.

What is the estimated delivery time for KI-TOX-A3?

Estimated delivery time for KI-TOX-A3 is approximately 10 business day(s), depending on your location.

KI-TOX-A3

Product Specifications

CAS Number

1351116-34-1

Target

Histone Acetyltransferase

Related Pathways

Chromatin/Epigenetic

Bioactivity

KI-TOX-A3 is a selective protein-protein interaction (PPI) inhibitor targeting the TOX protein, with an IC50 value of 0.51 μM for the TOX-KAT7 interaction. It promotes proteasomal degradation of TOX, restores KAT7-mediated H3K14 acetylation, reverses CD8+ T cell exhaustion, and inhibits proliferation of T-cell acute lymphoblastic leukemia (T-ALL) cells. KI-TOX-A3 holds potential for research in hematological malignancies, including T-ALL.