5α-Androstan-3α-ol
Product Specifications
CAS Number
7657-50-3
Target
GABA Receptor, Others
Related Pathways
Membrane transporter/Ion channel, Others, Neuroscience
Bioactivity
5α-Androstan-3α-ol is a γ-aminobutyric acid (GABA) receptor agonist. It inhibits the transcriptional activity of the orphan nuclear receptor CAR (constitutive androstane receptor) . By binding to CAR and promoting its dissociation from coactivator proteins, 5α-Androstan-3α-ol negatively regulates CAR's activity. This compound is useful for studying hormone metabolism and drug detoxification mechanisms mediated by nuclear receptors.
Smiles
C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)CCC4)[H])(CC[C@]1(C[C@H](O)CC2)[H])[H])[H]
Molecular Formula
C19H32O
Molecular Weight
276.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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