Clonixeril
Product Specifications
CAS Number
21829-22-1
Target
STING
Related Pathways
Immunology/Inflammation
Bioactivity
Clonixeril (NSC 335504) is a non-nucleotide modulator of hSTING. It exhibits weak agonistic activity at micromolar concentrations and can antagonize the hSTINGWT pathway at low femtomolar (10^-15 M) and even attomolar (10^-18 M) concentrations in some cases. Clonixeril inhibits hSTING oligomerization at concentrations ranging from 1 aM to 1 pM.
Smiles
O=C(OCC(O)CO)C1=CC=CN=C1NC=2C=CC=C(Cl)C2C
Molecular Formula
C16H17ClN2O4
Molecular Weight
336.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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