What is the catalog number for NF-κB degrader 1?

The catalog number for NF-κB degrader 1 is T210896.

What sizes are available for NF-κB degrader 1?

NF-κB degrader 1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does NF-κB degrader 1 come in?

NF-κB degrader 1 is available in 2 different pack sizes.

Is NF-κB degrader 1 in stock?

NF-κB degrader 1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NF-κB degrader 1?

NF-κB degrader 1 is manufactured by Molfinity.

What is the estimated delivery time for NF-κB degrader 1?

Estimated delivery time for NF-κB degrader 1 is approximately 10 business day(s), depending on your location.

NF-κB degrader 1

Product Specifications

Target

NF-κB

Related Pathways

NF-κB

Bioactivity

NF-κBdegrader 1 (Compound MD-1) is an NF-κB1p105 subunit degrader. It exhibits anti-inflammatory properties, with an IC50 of 2.02 μM for inhibiting TNF-α and 5.40 μM for inhibiting NO. NF-κBdegrader 1 induces p105 degradation via the Cullin-RING ligase (CRL) SCFBTCP, thereby inhibiting NF-κB transcriptional activity. This compound shows potential for research in inflammation-related diseases.