What is the catalog number for RUNX1/ETO-IN-1?

The catalog number for RUNX1/ETO-IN-1 is T210892.

What sizes are available for RUNX1/ETO-IN-1?

RUNX1/ETO-IN-1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does RUNX1/ETO-IN-1 come in?

RUNX1/ETO-IN-1 is available in 2 different pack sizes.

Is RUNX1/ETO-IN-1 in stock?

RUNX1/ETO-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures RUNX1/ETO-IN-1?

RUNX1/ETO-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for RUNX1/ETO-IN-1?

Estimated delivery time for RUNX1/ETO-IN-1 is approximately 10 business day(s), depending on your location.

RUNX1/ETO-IN-1

Product Specifications

CAS Number

923865-06-9

Target

Apoptosis, Others

Related Pathways

Others, Apoptosis

Bioactivity

RUNX1/ETO-IN-1 is an inhibitor targeting the oncogenic fusion protein RUNX1-ETO, specifically affecting the NHR2 oligomerization domain. It binds directly to NHR2 (KD, app = 39 μM) . By inducing apoptosis and promoting differentiation, RUNX1/ETO-IN-1 exhibits antileukemic activity in RUNX1/ETO translocation acute myeloid leukemia (AML) cells. Its near-neutral charge under physiological pH conditions grants it excellent cell membrane permeability.