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HDAC6-IN-61

Product Specifications

Target

Microtubule Associated, ERK, GPCR, HDAC

Related Pathways

Chromatin/Epigenetic, Endocrinology/Hormones, Cytoskeletal Signaling, DNA Damage/DNA Repair, MAPK, GPCR/G Protein

Bioactivity

HDAC6-IN-61 (Compound 4e) is an HDAC6 inhibitor with an IC50 of 73 nM, demonstrating greater selectivity compared to other HDAC isomers. It also acts as an activator of GPR40. HDAC6-IN-61 can increase the acetylation of tubulin and phosphorylation levels of ERK. This compound is relevant for studying neuroinflammation, including Alzheimer's disease.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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