AAK1-IN-8
Product Specifications
CAS Number
2969205-90-9
Target
Serine/threonin kinase|||AAK1 (AP2 associated kinase 1)
Related Pathways
Cell Cycle/Checkpoint|||Neuroscience|||Metabolism
Bioactivity
AAK1-IN-8 (Compound 18) is a broad-spectrum NAK inhibitor. It effectively inhibits AAK1 and GAK with EC50 values of 50 nM and 190 nM, respectively, and prevents the phosphorylation of the AP2-µ2 subunit at threonine 156 (T156) .
Smiles
O=C(NCC=1C=CC=CC1)C2=CC=C3C=C2OCCOCCN=C4C=CN5N=CC3=C5N4
Molecular Formula
C24H23N5O3
Molecular Weight
429.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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